Detection of exosomal miR-18a and miR-222 levels in Egyptian patients with hepatic cirrhosis and hepatocellular carcinoma.
Eman A ElghorouryEsmat E AbdelghaffarEman AwadallahSolaf A KamelDina KandilEman M HassanMirhane HassanMahmoud M KamelMohammed M GomaaLamiaa A FathallaPublished in: International journal of immunopathology and pharmacology (2022)
miR-18a and miR-222 were significantly discriminative markers between patients with liver cirrhosis and HCC and healthy individuals. Therefore, they have a prognostic rather than a diagnostic value. Moreover, miR-18a and miR-222 could be useful in identifying liver injuries, including fibrosis and cirrhosis.