Hnf4a Is Required for the Development of Cdh6-Expressing Progenitors into Proximal Tubules in the Mouse Kidney.

Sierra S MarableEunah ChungJoo-Seop Park

Published in: Journal of the American Society of Nephrology : JASN (2020)

Hnf4a promotes the differentiation of PT progenitors into mature PT cells by regulating the expression of genes associated with reabsorption, the major function of PT cells.

Keyphrases

induced apoptosis
cell cycle arrest
nuclear factor
cell death
inflammatory response
wild type