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Demonstration of real-time positron emission tomography biology-guided radiotherapy delivery to targets.

Oluwaseyi M OderindeManoj NarayananPeter OlcottYevgen VoronenkoJon BurnsShiyu XuLing ShaoKarine A Al FeghaliShervin M ShirvaniMurat SurucuGopinath Kuduvalli
Published in: Medical physics (2024)
This phantom-based study demonstrated that PET signals from PET-avid tumors can be utilized to direct real-time dose delivery to the tumor accurately, which is comparable to the dosimetric accuracy of SBRT. Furthermore, BgRT delivered a PET-signal controlled dose to the moving target, equivalent to the dose distribution to the static target. A future study will compare the performance of BgRT with conventional image-guided radiotherapy.
Keyphrases
  • positron emission tomography
  • computed tomography
  • radiation therapy
  • pet ct
  • pet imaging
  • early stage
  • locally advanced
  • radiation induced
  • magnetic resonance imaging
  • monte carlo