Serum neurofilament light chain: a novel biomarker for early diabetic sensorimotor polyneuropathy.

Haifa MaalmiAlexander StromAgnese Petrera Stefanie M Hauck Klaus Strassburger Oliver Kuß Oana Patricia Zaharia Gidon J Bönhof Wolfgang Rathmann Sandra Trenkamp Volker Burkart Julia Szendroedi Dan Ziegler Michael Roden Christian Herdernull null

Published in: Diabetologia (2022)

Our findings in individuals recently diagnosed with diabetes provide new evidence associating higher serum NFL levels with DSPN and peripheral nerve dysfunction. The present study advocates NFL as a potential biomarker for DSPN.

Keyphrases

peripheral nerve
type diabetes
oxidative stress
functional connectivity
glycemic control
metabolic syndrome
adipose tissue
insulin resistance