Efficacy of steroid therapy for improving native liver survival after pediatric acute liver failure with immune activation.

Hiroshi OueEitaro HiejimaHideaki OkajimaTatsuya OkamotoEri OgawaElena Yukie UebayashiEtsuro HatanoTakenori SugaYotaro HanamiKazushige AshinaShinichi KaiTsuyoshi SogoAyano InuiTakeshi Matsubara Kaoru SakaiMotoko YanagitaHironori HagaSachiko MinamiguchiYosuke YamadaHiroshi NihiraKazushi IzawaTakahiro YasumiJunko Takita

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)

Steroid therapy is effective for PALF patients with liver inflammation; however, liver transplantation should be prioritized for young children with ALF accompanied by severe coagulopathy or massive hepatic necrosis.

Keyphrases

liver failure
hepatitis b virus
oxidative stress
early onset
stem cells
acute respiratory distress syndrome
smoking cessation