White Matter Hyperintensities, Dopamine Loss, and Motor Deficits in De Novo Parkinson's Disease.

Seong Ho JeongHye Sun LeeJin Ho JungKyoungwon Baik Yang Hyun Lee Han Soo YooYoung H SohnSeok Jong Chung Phil Hyu Lee

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

This study suggests that the detrimental effect of white matter hyperintensities on parkinsonian motor symptoms is more relevant and independent for axial motor impairments in the status of mildly decreased striatal dopamine transporter availability. © 2021 International Parkinson and Movement Disorder Society.

Keyphrases

white matter
multiple sclerosis
uric acid
traumatic brain injury
parkinson disease
physical activity
metabolic syndrome
prefrontal cortex
depressive symptoms