Prediction of treatment responses to neoadjuvant chemotherapy in triple-negative breast cancer by analysis of immune checkpoint protein expression.

Yuka AsanoShinichiro KashiwagiWataru GotoKoji TakadaKatsuyuki TakahashiTamami MorisakiHisakazu FujitaTsutomu TakashimaShuhei TomitaMasahiko OhsawaKosei HirakawaMasaichi Ohira

Published in: Journal of translational medicine (2018)

PD-1 and PD-L1 expressions may be useful as biomarkers to predict treatment responses to NAC in breast cancer. Above all, PD-L1 expression may also be useful as biomarkers for more effective chemotherapy in TNBC.

Keyphrases

neoadjuvant chemotherapy
locally advanced
lymph node
squamous cell carcinoma
radiation therapy
early stage
combination therapy
chemotherapy induced