Evaluation of new leptospiral antigens for the diagnosis of equine leptospirosis: An approach using pan-genomic analysis, reverse vaccinology and antigenic selection.
Tiago J ZilchJen-Jie LeeGustavo C BressanSean P McDonoughHussni O MohammedThomas J DiversYung-Fu ChangPublished in: Equine veterinary journal (2020)
The new leptospiral antigens described in this research could increase the sensitivity and specificity of ELISA for detection of Leptospira exposure and the detection of leptospirosis in horses along with support from other clinical signs. Some of these new antigens might be used to improve the detection of infecting serovar.