Ultrasensitive quantitation of FLT3-ITD mutation in patients with acute myeloid leukemia using ddPCR.
Amir Asri KojabadRouzbeh ChegeniShaharbano RostamiFarhad ZakerMajid SafaPublished in: Molecular biology reports (2023)
This study demonstrates the feasibility of using the described in-house ddPCR method to quantify the FLT3-ITD mutation and measure FLT3-ITD AR in AML patients.
Keyphrases
- acute myeloid leukemia
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- ms ms
- prognostic factors
- gold nanoparticles
- liquid chromatography tandem mass spectrometry
- patient reported outcomes
- label free
- tyrosine kinase
- liquid chromatography