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Second malignancy in non-small cell lung cancer (NSCLC): prevalence and overall survival (OS) in routine clinical practice.

Martin FaehlingBirgit SchwenkSebastian KrambergSabine FallscheerMatthias LeschkeJörn SträterRobert Eckert
Published in: Journal of cancer research and clinical oncology (2018)
Prior or synchronous second malignancies are common at diagnosis of NSCLC. The sites reflect the high proportion of smokers in the population. The earlier stage of NSCLC with a second malignancy might be attributed to chance finding of NSCLC during follow-up. The second malignancy does not affect OS of NSCLC. Therefore, the exclusion of patients with second malignancies from NSCLC trials should be reconsidered.
Keyphrases
  • small cell lung cancer
  • advanced non small cell lung cancer
  • clinical practice
  • brain metastases
  • epidermal growth factor receptor
  • risk factors