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Transcriptomic profiling in Cutaneous Leishmaniasis patients.

Nasrin MasoudzadehAmir MizbaniSima Rafati
Published in: Expert review of proteomics (2020)
In this review, we focus on the transcriptomics studies that have been performed so far on human blood or tissue-driven samples to investigate Leishmania parasites interplay with the CL patients. Further, we summarize microarray and RNA-seq studies associated with lesion biopsies of CL patients to discuss how current whole genome analysis along with systems biology approaches have developed novel CL biomarkers for further applications, not only for research, but also for accelerating vaccine development.
Keyphrases
  • end stage renal disease
  • rna seq
  • single cell
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • peritoneal dialysis
  • patient reported outcomes