Associations between mitochondrial copy number, exercise capacity, physiologic cost of walking, and cardiac strain in young adult survivors of childhood cancer.
Amy M BerkmanChelsea G GoodenoughPaul DurakiewiczCarrie R HowellZhaoming WangJohn EastonHeather L MulderGregory T ArmstrongMelissa M HudsonMondira KunduKirsten K NessPublished in: Journal of cancer survivorship : research and practice (2024)
These findings demonstrate a potential role for mtDNA-CN as a biomarker of early cardiac dysfunction in this population.