Increased epithelial backscatter: A novel finding in subclinical and clinical keratoconus.

Increased epithelial backscatter and a strong correlation with anterior stromal backscatter in the KC groups were consistent with the epithelium-stroma interaction involved in KC pathogenesis. Single-point backscatter analysis can be used with point clouds to construct epithelial and stromal backscatter maps in Pentacam to aid the detection of KC as a novel feature.