In Vitro Comparative Study of Platelets Treated with Two Pathogen-Inactivation Methods to Extend Shelf Life to 7 Days.
Nicolas MalvauxFanette DefraigneStyliani BartzialiCamille BelloraKathleen MommaertsFay BetsouAnne SchuhmacherPublished in: Pathogens (Basel, Switzerland) (2022)
Results suggest that RF-PI treatment has a higher deleterious impact on in vitro platelet quality compared to AM-PI, but we observed higher loss of platelets with AM-PI due to the post-illumination amotosalen adsorption step. If 7-day storage is needed, it can only be achieved with AM-PI, based on our quality criteria.