Peripheral granular lymphocytopenia and dysmorphic leukocytosis as simple prognostic markers in COVID-19.

Yuki HoriuchiFumiaki HayashiYosuke IwasakiAkihiko MatsuzakiKumiko NishibeKimiko KaniyuSetsuko MarutaniKaori SaitoSachiko MatsuokaKinya UchihashiTakashi MiidaTomohiko AiYoko Tabe

Published in: International journal of laboratory hematology (2021)

Basic PB examination can be useful to predict the prognosis of COVID-19, by detecting SARS-CoV-2 infection-induced multi-lineage changes in blood cell counts and morphological anomalies. These changes were dynamically correlated with disease severity and may be associated with disruption of hematopoiesis and the immunological system due to bone marrow stress in severe infection.

Keyphrases

coronavirus disease
sars cov
bone marrow
respiratory syndrome coronavirus
single cell
mesenchymal stem cells
high glucose
heavy metals
drug induced
early onset
diabetic rats
endothelial cells
stem cells
risk assessment
stress induced
cell fate