Three-dimensional bipedal DNA walker enabled logic gates responding to telomerase and miRNA.
Xin LiuFanyu MengRui SunKang-Nan WangZhi-Qiang YuPeng MiaoPublished in: Chemical communications (Cambridge, England) (2021)
In this work, we have developed a simple and reliable platform for simultaneous analysis of telomerase and miRNA. A three-dimensional bipedal DNA walking strategy is designed utilizing gold nanoparticles and MnO2 nanosheets. Given the merits of fast, sensitive and selective analysis, the developed method has great potential application in early clinical diagnosis.