DNA methylation of the Lamin A/C gene is associated with congenital heart disease.

Nandini Mukherjee Elijah Holbrook BolinAmna QasimMohammed S OrloffPhilip J Lupo Wendy N Nembhard

Published in: Birth defects research (2024)

We identify statistically significant differences in LMNA DNAm between CHD cases and controls. Future studies should investigate the role of maternal LMNA DNAm in CHD development.

Keyphrases

dna methylation
genome wide
nk cells
muscular dystrophy
copy number
current status
gene expression
birth weight
case control
pregnancy outcomes
genome wide identification
duchenne muscular dystrophy
weight gain