GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic features.
Lochlan J FennellDiane M McKeoneNeal I WalkerMark L BettingtonBarbara A LeggettVicki L J WhitehallPublished in: Histopathology (2017)
GNAS mutations contribute significantly to the development of a subset of serrated adenomas and CRCs.