Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients.

Edgars EndzeliņšAndreas BergerVita MelneCristina Bajo-SantosKristīne SoboļevskaArtūrs ĀbolsMarta RodriguezDaiga ŠantareAnastasija RudņickihaVilnis LietuvietisAlicia LlorenteAija Linē

Published in: BMC cancer (2017)

This study demonstrates that for some miRNA biomarkers EVs provide a more consistent source of RNA than whole plasma, while other miRNAs show better diagnostic performance when tested in the whole plasma.

Keyphrases

cell free
prostate cancer
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
radical prostatectomy
label free
patient reported
circulating tumor