TNF-α From the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy.

Yi Wen Xiaohan Lu Jamie R PrivratskyJiafa RenSaba AliBo Yang Nathan P Rudemiller Jiandong Zhang Sergei A Nedospasov Steven D Crowley

Published in: Kidney360 (2023)

TNF from the proximal but not the distal nephron propagates kidney injury and fibrogenesis in aristolochic acid nephropathy in part by inducing G2/M cell cycle arrest of TECs.

Keyphrases

cell cycle arrest
rheumatoid arthritis
cell death
pi k akt
minimally invasive