EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells.

Donatienne d'HoseBarbara MathieuLionel Mignion Micael HardyOlivier OuariBénédicte F Jordan Pierre Sonveaux Bernard Gallez

Published in: Molecules (Basel, Switzerland) (2022)

MM10 altered the OCR in prostate cancer cells. The effect of MM10 on the superoxide level was dependent on the antioxidant capacity of cell line. In vivo, MM10 alleviated tumor hypoxia, yet without consequence in terms of response to irradiation.

Keyphrases

endothelial cells
hydrogen peroxide