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Mir22hg facilitates ferritinophagy-mediated ferroptosis in sepsis by recruiting the m6A reader YTHDC1 and enhancing Angptl4 mRNA stability.

Wenlong DengLiang ZhongShupei YeJiajing LuoGuobin RenJunhao HuangXiaolei Zhuang
Published in: Journal of bioenergetics and biomembranes (2024)
Mir22hg contributed to in ferritinophagy-mediated ferroptosis in sepsis via recruiting the m6A reader YTHDC1 and strengthening Angptl4 mRNA stability, highlighting that Mir22hg may be a potential target for sepsis treatment based on ferroptosis.
Keyphrases
  • cell proliferation
  • long non coding rna
  • cell death
  • long noncoding rna
  • septic shock
  • acute kidney injury
  • intensive care unit
  • fluorescent probe
  • living cells
  • aqueous solution