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Temporal evolution of new T1-weighted hypo-intense lesions and central brain atrophy in patients with a first clinical demyelinating event treated with subcutaneous interferon β-1a.

Hugo VrenkenMarco BattagliniM L de VosG J NagtegaalBernardo Corrêa de Almeida TeixeiraAndrea SeitzingerDominic JackMaria Pia SormaniBernard M J UitdehaagA VersteegGiancarlo ComiLudwig KapposNicola De StefanoFrederik Barkhof
Published in: Journal of neurology (2023)
In patients with an FCDE, treatment with sc IFN β-1a tiw for 24 months reduced the number of new lesions evolving into black holes.
Keyphrases
  • dendritic cells
  • magnetic resonance
  • white matter
  • resting state
  • computed tomography
  • multiple sclerosis
  • cerebral ischemia
  • replacement therapy