Human amniotic membrane extracellular matrix scaffold for dental pulp regeneration in vitro and in vivo.
Hengameh BakhtiarAzin AshooriSarah RajabiMohamad Pezeshki-ModaressAlireza AyatiMohammad Reza MousaviMohammad Reza ElliniAmir KamaliAmir AzarpazhoohAnil KishenPublished in: International endodontic journal (2021)
The 30 mg/ml HAM ECM scaffold had optimal physical properties and better supported hDPSC migration. The HAM ECM scaffold did not interfere with formation of pulp-like tissue and revascularization within the root canal when employed as both cell-free and cell-loaded scaffold. These results highlight the potential of HAM ECM membrane for further investigations in regenerative endodontics.