Colorectal Cancer Risk by Genetic Variants in Populations With and Without Colonoscopy History.
Feng GuoXuechen ChenJenny Chang-ClaudeMichael HoffmeisterHermann BrennerPublished in: JNCI cancer spectrum (2021)
Predictive performance of PRS may be underestimated in populations with widespread use of colonoscopy. Future studies using PRS to develop CRC prediction models should carefully consider colonoscopy history to provide more accurate estimates.