Changes in extracellular matrix in subcutaneous small resistance arteries of patients with essential hypertension.
Gaia FaveroAnna PainiCarolina De CiuceisLuigi F RodellaEnrico MorettiEnzo PorteriClaudia RossiniSilvia MinistriniLeonardo SolainiCaletti StefanoMaria Antonietta CoschignanoValeria BramiAlina PetelcaMatteo NardinIlenia ValliGuido A M TiberioFrancesca BonominiClaudia Agabiti RoseiNazario PortolaniDamiano RizzoniRita RezzaniPublished in: Blood pressure (2018)
Our results indicate that, in small resistance arteries of patients with essential hypertension, a relevant fibrosis may be detected; fibronectin and TGF-β1 tunica media content is increased, while laminin and emilin-1 content is decreased; these changes might be involved in the development of small resistance artery remodeling in humans.
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