Precision Medicine is a reality in selected medical areas, as oncology, or in excellent healthcare structures, but it is still far to reach million patients who could benefit from this medical concept. Here, we sought to highlight how the time is ripe to achieve horizontal delivery to a significant larger audience of patients, represented by the poly-treated patients. Combination therapies are frequent (especially in the elderly, to treat comorbidities) and are related to decreased drug safety and efficacy, disease's exacerbation, additional treatments, hospitalization. But the recent development and validation of bioinformatic tools, aimed to automatic evaluation and optimization of poly-therapies, according to the unique individual characteristics (including genotype), is ready to change the daily approach to pharmacological prescription.
Keyphrases
- end stage renal disease
- healthcare
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- chronic obstructive pulmonary disease
- prognostic factors
- emergency department
- machine learning
- deep learning
- intensive care unit
- high resolution
- social media
- extracorporeal membrane oxygenation
- middle aged
- health information
- virtual reality
- clinical evaluation