Regional changes in intestinal permeability in cirrhosis are associated with mucosal bacteria.
Patricia Pringle BloomKrishna RaoChristine M BassisBorko NojkovVincent B YoungAnna S F LokPublished in: Hepatology communications (2023)
Duodenal epithelial permeability was higher, and mucosal bacteria alpha diversity was lower in cirrhosis compared to controls, while no such differences were seen in the ileum or colon. Specific bacteria were associated with epithelial permeability and future hepatic decompensation.
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