Impact of atrial fibrillation on platelet gene expression.

Waldemar E WysokinskiAlfonso TafurNaser AmmashSamuel J AsirvathamYanhong WuIzabella Gosk-BierskaDiane E GrillJoshua P SlusserJozef MrukRobert D McBane

Published in: European journal of haematology (2017)

Platelets are capable to respond to the circulatory environment of NVAF by altering transcript and changing prothrombotic status. This shows platelet potential for molecular "reprogramming" possibly induced by flow disturbances of NVAF.

Keyphrases

gene expression
atrial fibrillation
dna methylation
heart failure
left atrial
rna seq
left atrial appendage
percutaneous coronary intervention
direct oral anticoagulants
left ventricular
climate change
coronary artery disease
mitral valve
single cell
red blood cell