Focal ischemic stroke leads to lung injury and reduces alveolar macrophage phagocytic capability in rats.
Cynthia S SamaryAlane B RamosLígia A MaiaNazareth N RochaCíntia L SantosRaquel F MagalhãesAmanda L ClevelarioPedro M Pimentel-CoelhoRosália Mendez-OteroFernanda F CruzVera L CapelozziTatiana P T FerreiraThea KochMarcelo Gama de AbreuClaudia C Dos SantosPaolo PelosiPedro L SilvaPatricia Rieken Macêdo RoccoPublished in: Critical care (London, England) (2018)
In rats, focal ischemic stroke is associated with brain-lung crosstalk, leading to increased pulmonary damage and inflammation, as well as reduced alveolar macrophage phagocytic capability, which seems to be promoted by systemic inflammation.