Payer decision making for next-generation sequencing-based genetic tests: insights from cell-free DNA prenatal screening.

Andrew P Dervan Patricia A DeverkaJulia R TrosmanChristine B Weldon Michael P DouglasKathryn A Phillips

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2016)

Payers utilized the standard evidentiary framework (AV/CV/CU) when evaluating cfDNA screening but varied in their interpretation of the sufficiency of the evidence. Professional guidelines, large CV studies, and decision analytic models regarding health outcomes appeared highly influential in coverage decisions.Genet Med advance online publication 22 September 2016.

Keyphrases

decision making
copy number
pregnant women
social media
health information
gene expression
case control
affordable care act
cell free