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Reduction of the survival time of pig xenotransplants by porcine cytomegalovirus.

Joachim Denner
Published in: Virology journal (2018)
Although it is still unknown whether PCMV infects primate cells including human cells, indirect mechanism of the virus infection may cause reduction of the xenotransplant survival in future clinical trials and therefore PCMV has to be eliminated from donor pigs.
Keyphrases
  • clinical trial
  • induced apoptosis
  • free survival
  • cell cycle arrest
  • epstein barr virus
  • current status
  • signaling pathway
  • study protocol