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Loss of CEACAM1 in hepatocytes causes hepatic fibrosis.

Sobia ZaidiSuman AsallaHarrison T MuturiLucia RussoRaziyeh AbdolahipourGetachew Debas BelewMaria Benitez IglesiasMary FeraudoLensay LeonEnoch KuoXiuli LiuSivarajan KumarasamyHilda E GhadiehCara Gatto-WeisAli ZarrinparSergio DuarteSonia M Najjar
Published in: European journal of clinical investigation (2024)
mice assigned a key role to CEACAM1 loss from hepatocytes in hepatic fibrosis independently of other liver cells.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • liver injury
  • high fat diet induced
  • liver fibrosis
  • oxidative stress
  • cell death
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • insulin resistance
  • pi k akt