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KA-104, a new multitargeted anticonvulsant with potent antinociceptive activity in preclinical models.

Krzysztof KamińskiSzczepan MogilskiMichał AbramAnna RapaczGniewomir LataczBartłomiej SzulczykMaria WalczakKamil KuśKarolina MatyjaszczykRafał M Kamiński
Published in: Epilepsia (2020)
The results reported herein indicate that KA-104 is a new wide-spectrum multitargeted anticonvulsant with favorable in vitro ADME-Tox properties. Importantly, this compound may also prove to become an interesting and hopefully more effective therapeutic option for treatment of neuropathic pain.
Keyphrases
  • neuropathic pain
  • spinal cord
  • spinal cord injury
  • anti inflammatory
  • molecular docking
  • cell therapy
  • combination therapy
  • mesenchymal stem cells