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Energy balance-related factors and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status.

Josien C A JenniskensKelly OffermansColinda C J M SimonsIryna V SamarskaGregorio E FazziJaleesa R M van der MeerKim M SmitsLeo J SchoutenMatty P WeijenbergHeike I GrabschPiet A van den Brandt
Published in: Journal of cancer research and clinical oncology (2022)
In men, associations did not vary according to molecular features. In women, a role of KRAS mutations in the etiological pathway between adiposity and colon cancer is suggested, and of PIK3CA mutations between physical activity and colon cancer.
Keyphrases
  • physical activity
  • wild type
  • insulin resistance
  • protein kinase
  • type diabetes
  • metabolic syndrome
  • pregnant women
  • single molecule
  • weight loss
  • metastatic colorectal cancer