Assessment of Developmental and Reproductive Fitness of Dengue-Resistant Transgenic Aedes aegypti and Improvement of Fitness Using Antibiotics.
Hewawasam Patuwatha Badathuruge Kalindu Dulanja RamyasomaYasanthi Illika Nilmini Silva GunawardeneMenaka HapugodaRanil Samantha DassanayakePublished in: BioMed research international (2021)
Our data indicate that the transgenic mosquito produced had a reduction of the fitness parameters and it may lead to a subsequent reduction of transgenic vector density over the generations in field applications. However, antibiotics of co-trimoxazole, amoxicillin, and doxycycline have shown the improvement of fitness parameters indicating the usefulness in field release of transgenic mosquitoes.