Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs.
Xiaofeng WangChang WangXiaowei ZhangRuixi HuaLu GanMingzhu HuangLiqin ZhaoSujie NiWei-Jian GuoPublished in: Journal of hematology & oncology (2016)
Bmi-1 positively regulates stem cell-like properties via upregulating miR-21, and miR-34a negatively regulates stem cell-like characteristics by negative feedback regulation of Bmi-1 in gastric cancer. Bmi-1 upregulates miR-21 and miR-34a by activating AKT-NF-kB pathway.