Neuroprotective effects of maternal melatonin administration in early-onset placental insufficiency and fetal growth restriction.
Atul MalhotraAnna K A A RochaTamara YawnoAmy E SutherlandBeth J AllisonIlias NitsosYen PhamGraham JenkinMargie Castillo-MelendezSuzanne L MillerPublished in: Pediatric research (2024)
Maternal melatonin administration might lead to neuroprotection in the growth-restricted fetus, possibly via dampening neuroinflammation and enhancing myelination. This preclinical study adds to the body of work on this topic, and informs clinical translation. Neuroprotection likely to improve long-term outcomes of this vulnerable infant group.