Effects of Perilla frutescens Var. Acuta in Busulfan-Induced Spermatogenesis Dysfunction Mouse Model.

Hyung Jong Nam Min Jung Park Bo Sun Joo Yean Kyoung Koo Suk-Jin Kim Sang-Don Lee Hyun Jun Park

Published in: The world journal of men's health (2024)

This study shows that PFA exerts a protective effect against testicular damage by attenuating OS induced by busulfan. Our results suggest that PFA is a potentially relevant drug used to decrease the side effects induced by busulfan on testicular function and sperm during cancer chemotherapy.

Keyphrases

mouse model
allogeneic hematopoietic stem cell transplantation
oxidative stress
germ cell
papillary thyroid
diabetic rats
drug induced
high glucose
squamous cell carcinoma
emergency department
acute myeloid leukemia
acute lymphoblastic leukemia
childhood cancer
stress induced
chemotherapy induced