Transition-Metal-Catalyzed Regioselective Functionalization of Monophosphino-o-Carboranes.
Zi-Yang ZhangXuepeng ZhangJia YuanChang-Duo YueSixuan MengJian ChenGuang-Ao YuChi-Ming ChePublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)
A facile approach to the synthesis of diaryl- and dialkyl-substituted monophosphino-o-carboranes by rhodium(I)-catalyzed phosphine-directed B3,6 -H activation has been developed for the first time. Upon switching rhodium(I) to palladium(II), C-arylated and B6 -halogenated products were obtained by using tBuOLi and Li2 CO3 as base, respectively. These discoveries provide some simple and efficient approaches to the modification of monophosphino-o-carboranes.