The relationship between radiation dose and bevacizumab-related imaging abnormality in patients with brain tumors: A voxel-wise normal tissue complication probability (NTCP) analysis.

Mia SalansJordan HouriRoshan KarunamuniAustin HopperRachel DelfantiTyler M SeibertNaeim BahramiYasamin SharifzadehCarrie McDonaldAnders DaleVitali MoiseenkoNikdokht FaridJona A Hattangadi-Gluth

Published in: PloS one (2023)

BRIA is likely a radiation dose-dependent phenomenon in patients with brain tumors receiving bevacizumab and radiotherapy. The combination of radiation effects and tumor microenvironmental factors in potentiating BRIA in this population should be further investigated.

Keyphrases

metastatic colorectal cancer
high resolution
early stage
radiation induced
locally advanced
squamous cell carcinoma
fluorescence imaging
photodynamic therapy
rectal cancer