Potential predictors of severe cardiovascular involvement in Marfan syndrome: the emphasized role of genotype-phenotype correlations in improving risk stratification-a literature review.
Roland StenglBence AggMiklós PólosGábor MátyásGábor SzabóBéla MerkelyTamás RadovitsZoltán SzabolcsKálmán BenkePublished in: Orphanet journal of rare diseases (2021)
Data on promising biomarkers of severe aortic complications of MFS have been accumulating steadily. However, more unifying studies are required to further evaluate the applicability of the discussed predictors with the aim of improving the risk stratification and therefore the life expectancy and quality of life of MFS patients.
Keyphrases
- end stage renal disease
- case report
- ejection fraction
- newly diagnosed
- early onset
- peritoneal dialysis
- prognostic factors
- aortic valve
- heart failure
- electronic health record
- left ventricular
- drug induced
- risk assessment
- aortic dissection
- pulmonary hypertension
- machine learning
- coronary artery
- patient reported outcomes
- artificial intelligence