Evidence of Residual Ongoing Viral Replication in Chronic Hepatitis B Patients Successfully Treated With Nucleos(t)ide Analogues.

Tong YuMiaoqu ZhangHanyue ZhangJianming ZhengChuan ShenNing JiangLei ZouJing WangYiqi YuQiran ZhangShuili YuYanfang HuangYuxian HuangJi-Ming ZhangChao QiuWenhong ZhangZhefeng Meng

Published in: The Journal of infectious diseases (2023)

We conclude that even after prolonged treatment, a small proportion of the cccDNA reservoir is constantly replenished by continued low-level HBV replication, whereas a large proportion of the cccDNA reservoir persists over time.

Keyphrases

hepatitis b virus
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
sars cov
peritoneal dialysis
prognostic factors
patient reported outcomes
liver failure