Exploring the effect of ritonavir and TMC-310911 on SARS-CoV-2 and SARS-CoV main proteases: potential from a molecular perspective.

Opeyemi S Soremekun Kehinde Foluke Omolabi Adeniyi T Adewumi Mahmoud E S Soliman

Published in: Future science OA (2020)

Although there are conflicting clinical results on the therapeutic potency of RVT in the treatment of coronavirus disease 2019, our findings provided molecular insight into the binding mechanism of TMC-310911 and RVT with SARS-CoV-2 and SARS-CoV main proteases.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
single molecule
transcription factor
climate change
binding protein
smoking cessation