A typical atypical chronic myeloid leukemia.

Andrea GilioliAmbra PaoliniGoretta BonacorsiMario Luppi

Published in: Clinical case reports (2018)

In the context of leukocytosis due to increased number of neutrophils and their precursors, with significant dysgranulopoiesis and no or minimal basophilia and no or minimal monocytosis, the typical feature of "clumped" chromatin, in irregularly coarse compacted nuclei, should lead to suspect the diagnosis of atypical chronic myeloid leukemia.

Keyphrases

chronic myeloid leukemia
gene expression
molecular dynamics
dna damage
molecular dynamics simulations
machine learning
transcription factor
deep learning
oxidative stress
dna methylation