Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis.

Kai-Wei JiaRen-Qi YaoYi-Wen FanDing-Ji ZhangYe ZhouMin-Jun WangLi-Yuan ZhangYue DongZhi-Xuan LiSu-Yuan WangMu WangYun-Hui LiLu-Xin ZhangTing LeiLiang-Chen GuiShan LuYing-Yun YangSi-Xian WangYi-Zhi YuYong-Ming YaoJin Hou

Published in: Military Medical Research (2024)

A-modified Gpx4 mRNA, suggesting the potential clinical application of IFN-α in the prevention of hepatic ferroptosis during liver I/R injury.

Keyphrases

cell death
dendritic cells
binding protein
immune response
transcription factor
liver injury
human health
risk assessment