Enhanced gastric cancer growth potential of mesenchymal stem cells derived from gastric cancer tissues educated by CD4+ T cells.

Rongman XuXiangdong ZhaoYuanyuan ZhaoBin ChenLi SunChanggen XuBo ShenMei WangWenrong XuWei Zhu

Published in: Cell proliferation (2017)

This study showed that GC-MSCs are plastic. The immunophenotype of GC-MSCs stimulated by CD4+ T cells has major changes that may influence tumour cell growth. This research was based on the interaction between tumour cells, MSCs and immune cells, providing a new understanding of the development and immunotherapy of GC.

Keyphrases

mesenchymal stem cells
umbilical cord
gas chromatography
bone marrow
induced apoptosis
cell cycle arrest
gene expression
mass spectrometry
stem cells
cell proliferation
high resolution
human health