Optimum support by high-flow nasal cannula in acute hypoxemic respiratory failure: effects of increasing flow rates.

Tommaso MauriLaura AlbanCecilia TurriniBarbara CambiaghiEleonora CarlessoPaolo TacconeNicola BottinoAlfredo LissoniSavino SpadaroCarlo Alberto VoltaLuciano GattinoniAntonio PesentiGiacomo Grasselli

Published in: Intensive care medicine (2017)

In this cohort of patients with AHRF, an increasing HFNC flow rate progressively decreased inspiratory effort and improved lung aeration, dynamic compliance and oxygenation. Most of the effect on inspiratory workload and CO2 clearance was already obtained at the lowest flow rate.

Keyphrases

respiratory failure
extracorporeal membrane oxygenation
mechanical ventilation
acute respiratory distress syndrome
intensive care unit
blood flow
hepatitis b virus
sleep apnea
positive airway pressure