Cortical Anoxic Spreading Depolarization During Cardiac Arrest is Associated with Remote Effects on Peripheral Blood Pressure and Postresuscitation Neurological Outcome.
Sangwoo HanMayra Isabel ContrerasAfsheen BazrafkanMasih RafiShirin M DaraAni OrujyanAnais PanossianChristian CrouzetBeth LopourBernard ChoiRobert H WilsonYama AkbariPublished in: Neurocritical care (2022)
To our knowledge, this is the first study to quantify the relationship between peripheral blood pressure, cerebral hemodynamics and metabolism, and neurological outcome in anoxic SD. These results indicate that the characteristics of SD may not be limited to cerebral hemodynamics and metabolism but rather may also encompass changes in peripheral blood flow, possibly through a brain-heart connection, providing new insights into the role of anoxic SD in global ischemia and recovery.
Keyphrases
- blood pressure
- blood flow
- cerebral ischemia
- cardiac arrest
- subarachnoid hemorrhage
- chemotherapy induced
- hypertensive patients
- heart rate
- heart failure
- healthcare
- cardiopulmonary resuscitation
- brain injury
- white matter
- atrial fibrillation
- resting state
- skeletal muscle
- multiple sclerosis
- insulin resistance
- metabolic syndrome
- weight loss