A comparison of landmark methods and time-dependent ROC methods to evaluate the time-varying performance of prognostic markers for survival outcomes.
Aasthaa BansalPatrick J HeagertyPublished in: Diagnostic and prognostic research (2019)
We compared alternative summaries for quantifying a prognostic marker's time-varying performance. Although landmark-based predictions may be useful when patient predictions are needed at select times, a focus on incident events naturally facilitates evaluating trends in performance over time.